Login to ConnectWise as an Admin and select System -> Members -> API Members as shown below:
 

Click on + as shown below: 

Fill out all required fields and click Save button: Be sure to set the permission to "Admin".

Click on API Keys and then click on the + sign to add a new key: 

Give it a description and click Save:The keys will disappear after you click save and close so copy both now to a document or directly into Alert Manager before you save and close in ConnectWise. 

Now login to MSP Process and click on Integrations and click Add CRM
 

Select ConnectWise: 

Input the settings for your integration. Please note your URL and Company ID will be the same that you use to login to CW. Ours is a test system URL. 

Select your Ticketing Defaults